Onkar P Kulkarni Selected Research

vidofludimus

6/2010

4SC-101, a novel small molecule dihydroorotate dehydrogenase inhibitor, suppresses systemic lupus erythematosus in MRL-(Fas)lpr mice.

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Onkar P Kulkarni Research Topics

Disease

15	Inflammation (Inflammations) 02/2021 - 12/2008
12	Lupus Nephritis 12/2017 - 06/2007
8	Systemic Lupus Erythematosus (Libman-Sacks Disease) 04/2017 - 04/2010
7	Glomerulonephritis 12/2017 - 08/2007
7	Necrosis 12/2015 - 09/2009
4	Immune Complex Diseases (Immune Complex Disease) 11/2011 - 08/2007
3	Proteinuria 12/2017 - 07/2013
3	Albuminuria 10/2015 - 09/2009
3	Autoimmune Diseases (Autoimmune Disease) 02/2015 - 12/2008
3	Nephritis 11/2011 - 04/2009
2	Body Weight (Weight, Body) 10/2020 - 07/2011
2	Sepsis (Septicemia) 10/2020 - 09/2011
2	Acute Kidney Injury (Acute Renal Failure) 01/2016 - 04/2013
2	Atrophy 07/2013 - 01/2011
2	Renal Insufficiency (Renal Failure) 01/2013 - 07/2011
2	Virus Diseases (Viral Diseases) 09/2012 - 11/2009
2	Lung Diseases (Lung Disease) 11/2011 - 09/2011
2	Type 2 Diabetes Mellitus (MODY) 07/2011 - 07/2011
2	Splenomegaly 09/2009 - 12/2008
1	Dysbiosis 01/2017
1	Hereditary Nephritis (Alport Syndrome) 01/2017
1	Uremia 01/2017
1	Thrombotic Microangiopathies 10/2015
1	Kidney Cortex Necrosis 10/2015
1	Hypergammaglobulinemia (Hyperimmunoglobulinemia) 02/2015
1	Aneuploidy (Aneuploid) 07/2013
1	Fibrosis (Cirrhosis) 07/2013
1	Kidney Diseases (Kidney Disease) 07/2013
1	Reperfusion Injury 04/2013
1	Nephrocalcinosis 01/2013
1	Infections 12/2011
1	Skin Diseases (Skin Disease) 09/2011
1	Diabetic Nephropathies (Diabetic Nephropathy) 07/2011
1	Disease Progression 01/2011

Drug/Important Bio-Agent (IBA)

9	CytokinesIBA 02/2021 - 11/2009
6	AutoantibodiesIBA 04/2017 - 08/2007
5	Antigen-Antibody Complex (Immune Complex)IBA 12/2017 - 08/2007
4	ChemokinesIBA 12/2017 - 07/2011
4	Immunoglobulin G (IgG)IBA 10/2015 - 06/2007
4	Toll-Like Receptors (Toll-Like Receptor)IBA 05/2014 - 08/2007
4	DNA (Deoxyribonucleic Acid)IBA 11/2011 - 12/2008
3	Immunosuppressive Agents (Immunosuppressants)IBA 12/2017 - 04/2012
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 12/2017 - 07/2011
3	Chemokine CXCL12IBA 12/2017 - 07/2011
3	Interleukin-18 (Interleukin 18)IBA 12/2015 - 01/2011
3	RNA (Ribonucleic Acid)IBA 11/2011 - 08/2007
2	CarrageenanIBA 02/2021 - 10/2020
2	OxalatesIBA 02/2021 - 01/2016
2	LipopolysaccharidesIBA 10/2020 - 09/2009
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 12/2017 - 01/2016
2	EndotoxinsIBA 01/2017 - 01/2011
2	InflammasomesIBA 01/2016 - 01/2011
2	Toll-Like Receptor 2IBA 10/2015 - 09/2009
2	CreatinineIBA 07/2013 - 04/2012
2	nutlin 3IBA 07/2013 - 11/2011
2	Interleukin-6 (Interleukin 6)IBA 04/2013 - 08/2007
2	Interleukin-12 (IL 12)IBA 09/2011 - 09/2009
2	Viral RNAIBA 11/2009 - 08/2007
1	Methanol (Carbinol)IBA 02/2021
1	ethyl acetateIBA 02/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2017
1	Secretory Immunoglobulin A (SIgA)IBA 01/2017
1	CollagenIBA 01/2017
1	Coloring Agents (Dyes)IBA 01/2016
1	LymphokinesIBA 12/2015
1	Histones (Histone)IBA 10/2015
1	ElementsIBA 02/2015
1	RO5461111IBA 02/2015
1	cathepsin SIBA 02/2015
1	Immunoglobulin M (IgM)IBA 02/2015
1	Interleukin-22 (IL-22)IBA 05/2014
1	Urea (Carbamide)FDA LinkGeneric 07/2013
1	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2013
1	NitrogenIBA 07/2013
1	PTX3 proteinIBA 04/2013
1	Caspase 1 (ICE Protease)IBA 01/2013
1	Calcium OxalateIBA 01/2013
1	Interferon-alpha (Interferon Alfa)IBA 09/2012
1	Antiviral Agents (Antivirals)IBA 09/2012
1	Interleukin-10 (Interleukin 10)IBA 04/2012
1	Chaperonin 10IBA 04/2012
1	Interferon-gamma (Interferon, gamma)IBA 04/2012
1	Interleukin-1 Receptor-Associated KinasesIBA 12/2011
1	AutoantigensIBA 11/2011
1	Protein CIBA 09/2011
1	Complement C3 (C3 Complement)IBA 09/2011
1	Complement System Proteins (Complement)IBA 08/2011
1	Chemokine ReceptorsIBA 07/2011
1	LigandsIBA 07/2011
1	Blood Glucose (Blood Sugar)IBA 07/2011
1	Bacterial DNAIBA 01/2011
1	GuanineIBA 01/2011
1	Interleukin-1 (Interleukin 1)IBA 01/2011
1	antiglomerular basement membrane antibodyIBA 01/2011
1	CytosineIBA 01/2011
1	vidofludimusIBA 06/2010
1	Leflunomide (Arava)FDA LinkGeneric 06/2010
1	Dihydroorotate DehydrogenaseIBA 06/2010

Therapy/Procedure

2	Therapeutics 12/2017 - 01/2016
1	Oral Administration 10/2020